Gain- and loss-of-function in chick embryos by electroporation

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Gain- and loss-of-function in chick embryos by electroporation

It remained very difficult to manipulate gene expression in chick embryos until the advent of in ovo electroporation which enabled the induction of both gain-of-function, and recently loss-of-function, of a gene of interest at a specific developmental stage. Gain-of-function by electroporation is so effective that it has become widely adopted in developmental studies in the chick. Recently, it ...

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ژورنال

عنوان ژورنال: Mechanisms of Development

سال: 2004

ISSN: 0925-4773

DOI: 10.1016/j.mod.2004.05.013